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It wasn't until 1865 that Gregor Mendel first traced [inheritance pattern]?s of certain traits in pea plants and showed that they obeyed simple statistical rules. Although not all features show this Mendelian inheritance, his work acted as a proof that application of statistics to inheritance could be highly useful. Since that time many more complex forms of inheritance have been demonstrated. From his statistical analysis Mendel defined a concept that he described as an "allele" which was the fundamental unit of heredity. The term "allele" as Mendel used it is nearly synonymous with the term "gene", whilst the term "allele" now means a specific example of a particular gene. The significance of Mendel's work was not understood until early in the twentieth century, after his death, when his research was re-discovered by other scientists working on similar problems. |
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It wasn't until 1865 that Gregor Mendel first traced [inheritance pattern]?s of certain traits in pea plants and showed that they obeyed simple statistical rules. Although not all features show this Mendelian inheritance, his work acted as a proof that application of statistics to inheritance could be highly useful. Since that time many more complex forms of inheritance have been demonstrated. From his statistical analysis Mendel defined a concept that he described as an allele which was the fundamental unit of heredity. The term allele as Mendel used it is nearly synonymous with the term gene, whilst the term allele now means a specific example of a particular gene. The significance of Mendel's work was not understood until early in the twentieth century, after his death, when his research was re-discovered by other scientists working on similar problems. |
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Mendel was unaware of the physical nature of the gene. We now know that they are the information normally carried on DNA. Manipulation of the DNA can in turn alter the inheritance, and features of various organisms. This science which grew out of biochemistry and genetics is widely known as molecular biology. |
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Mendel was unaware of the physical nature of the gene. We now know that they are the information normally carried on DNA. Manipulation of the DNA can in turn alter the inheritance, and features of various organisms. This science which grew out of biochemistry and genetics is widely known as molecular biology. |
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:1859 Charles Darwin publishes The Origin of Species |
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:1928 [Frederick Griffith]? discoveres a hereditary molecule that is transmissible between bacteria (see Griffiths experiment) |
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:1944 Avery? isolates DNA as the genetic material (at that time called [transforming principle]?) |
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:1944 [Oswald Theodore Avery]?, [Colin McLeod]? and [Maclyn McCarty]? isolate DNA as the genetic material (at that time called [transforming principle]?) |
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:1950 [Erwin Chargaff]? shows that the four nucleotides are not present in nucleic acids in stable proportions |
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:1953 DNA structure is resolved to be a double helix? :1958 DNA is semiconservatively replicated |
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:1953 DNA structure is resolved to be a double helix? by James Watson and Francis Crick :1958 DNA is [semiconservatively replicated]? |
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:1977 DNA is sequenced? |
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:1977 DNA is sequenced |
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:See also : biology -- central dogma of genetics |
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:See also : biology -- central dogma of genetics |
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