[Home]History of Valproic Acid

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Revision 5 . . (edit) December 13, 2001 12:35 am by Malcolm Farmer [If that's its chemical name, the formula drawn seems Ok]
Revision 4 . . December 12, 2001 8:20 pm by (logged).253.39.xxx [mentioned formula is for Sodium salt - my chemistry is ancient, any chemists here to check?]
Revision 3 . . December 12, 2001 8:18 pm by (logged).253.39.xxx [copyedit, mentioned mood stabiliset]
Revision 2 . . (edit) December 12, 2001 7:08 pm by (logged).253.64.xxx
Revision 1 . . December 12, 2001 7:05 pm by (logged).253.64.xxx
  

Difference (from prior major revision) (minor diff, author diff)

Added: 2a3,4
Formula for the the sodium salt:


Changed: 5c7,10
A anticonvulsant? drug used in the treatment of epilepsy? to control absence seizures, tonic-clonic seizures ([grand mal]?), complex partial seizures, and the seizures associated with [Lennox-Gastaut syndrome]?. Also is used to prevent [migraine headache]?s, as a [mood stabiliser]? to treat bipolar disorders (acute uncomplicated mania, mixed state and rapid cycling), and for facial neuralgias.
It is an anticonvulsant? drug used in the treatment of epilepsy? to control absence seizures, tonic-clonic seizures ([grand mal]?), complex partial seizures, and the seizures associated with [Lennox-Gastaut syndrome]?. It is also used to prevent [migraine headache]?s, as a [mood stabiliser]? to treat bipolar disorders (acute uncomplicated mania, mixed state and rapid cycling), and for facial neuralgias.

Common side effects are weight gain, tremor, dizziness, sedation, headache, nausea, dyspepsia, and hair loss. Idiosyncratic side effects include the possibility of impaired liver function and jaundice; blood dyscrasia, especially thrombocytopenia (rare) and prolonged coagulation times. Possible teratogenic effect, it is known to cross the placenta and may cause congenital anomalies in the fetus (about 4-6% risk overall)


Removed: 7d11
Common side effects are weight gain, tremor, dizziness, sedation, headache, nausea, dyspepsia, and hair loss. Idiosyncratic side effects include the possibility of impaired liver function and jaundice; blood dyscrasia, especially thrombocytopenia (rare) and prolonged coagulation times; Possible teratogenic effect, it is known to cross the placenta and may cause congenital anomalies in the fetus (about 4-6% risk overall).

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