[Home]History of HIV

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Revision 4 . . (edit) November 21, 2001 9:54 pm by Magnus Manske [fixed links]
Revision 3 . . November 21, 2001 7:38 pm by Sodium [moved treatments from AIDS]
Revision 2 . . November 21, 2001 7:08 pm by Magnus Manske [+Kary Mullis theory (NPOV)]
Revision 1 . . November 21, 2001 3:48 pm by (logged).252.236.xxx
  

Difference (from prior major revision) (minor diff, author diff)

Changed: 1c1
HIV is the abbreviation for Human Immunodeficiency Virus, and describes a number of different kinds of viruses which attack the human immune system and which have been shown to cause Acquired Immune Deficiency Syndrome.
HIV is the abbreviation for Human Immunodeficiency Virus, and describes a number of different kinds of viruses which attack the human immune system and which have been shown to cause Acquired Immune Deficiency Syndrome.

Added: 3a4,17

Treatment




Patients today are given a rather complex regime of drugs which attack HIV at various stages in its life cycle. These are known as [antiretroviral drugs]?. They include:

* [Protease inhibitor]?s (PIs) inhibit production of protease?, an enzyme used directly by HIV, and so prevents virus replication.

* [Reverse transcriptase inhibitors]?s (RTIs) inhibit production of reverse transcriptase, an enzyme HIV needs to reproduce. Lack of this enzyme prevents HIV from building RNA and DNA. They come in three forms:

** [Non-nucleoside reverse transcriptase inhibitor]?s (NNRTIs)
** [Nucleoside analog reverse transcriptase inhibitor]?s (NARTIs)
** [Nucleotide analog reverse transcriptase inhibitor]?s (NtARTIs?)

There are many problems involved in establishing a course of treatment for HIV. Each effective drug comes with side effects, often serious and sometimes life-threatening in themselves. Common side effects include extreme nausea? and diarrhea?, liver damage and jaundice?. Any treatment requires regular blood tests to test for continued efficacy (in terms of T-cell? count and [viral load]?), and liver function.

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