Inosite triphosphate (short
InsP?3), together with diacylclycerole
?, is a
second messenger molecule used in
cellular
signal transduction. It is made from
[phosphatidyl inosite]?, a
phospholipid, that is located in the
plasma membrane, by
phospholipase C. Its main functions are to mobilize
Ca2+ from storage
organelles, to regulate [cell proliferation]
? and other cellular reactions. For example, in Drospohila
?, InsP
?3 is used for intracellular transduction of light recognition in
eye cells. It can be removed and reconstructed in the [inosite cycle]
?.