[Home]Scopolamine

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Scopolamine (C17H21NO4), usually Scopolamine Hydrobromide, is an alkaloid drug obtained from plants of the Solanaceae family (Nightshade), such as henbane? or [jimson weed]? (Datura sp.). Structurally similar to acetylcholine?.

In medicine, it can be used as an anticholinergic? with CNS depressant effects, though it can cause delirium? in the presence of pain, pupillary dilation, and cycloplegia?. When combined with morphine it produces a tranquilized state known as [twilight sleep]? and amnesia?, originally used in obstetrics it is now considered dangerous.

Used in ophthalmy? for cycloplegia? and mydriasis? in diagnostic procedures. In the treatment of iridocyclitis?. It is also an antiemetic?, antivertigo?, antispasmodic?, used as a pre-anesthetic? sedation and obstetric amnesia?, as an antiarrhythmic during anesthesia and for the prevention of [motion sickness]?.

An overdose can cause delirium?, delusion?s, paralysis, and stupor?.

The use of scopolamine as a truth drug was investigated by various intelligence agencies including the CIA during the 50s, however it was found that due to the hallucinogenic side-effects of the drug that the truth was prone to distortion and the project was subsequently abandoned.

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Last edited November 28, 2001 2:05 am by Lee Daniel Crocker (diff)
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