[Home]Cardiac glycoside

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Any drug used in the treatment of congestive cardiac failure (CCF) or cardiac arrhythmia, by inhibiting the Na+ / Ka + / ATP-ase pump. This inhibition increases the amount of Ca++ ions available for contraction and improves cardiac output and reduces distention of the heart.

It has an antiarrhythmic effect by prolonging the refractory period of the AV node (Atrio-ventricular), reducing the number of impulses reaching the ventricles. Cardiac output is restored but atrial fibrillation or atrial flutter are not abolished.

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Last edited December 2, 2001 11:14 pm by TwoOneTwo (diff)