[Home]History of Penicillin

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Revision 6 . . (edit) December 9, 2001 7:05 am by Bryan Derksen [fixed peptidoglycan link]
Revision 5 . . October 18, 2001 1:18 am by The Cunctator [*A stubby link to optical isomerism, would be better as a full sentence]
Revision 4 . . (edit) September 29, 2001 12:31 am by Firehawk [corrected links for Chain and Florey's names.]
  

Difference (from prior major revision) (minor diff, author diff)

Changed: 5c5
Penicllin works by inhibiting the formation of [peptidoglycan cross links]? in the bacterial cell wall by directly competing for the reaction site (the [beta-lactam ring]? of penicillin is a chemical analogue for the enzyme that links the peptidoglycan molecules in bacteria) and thus preventing the bacteria from multiplying (or rather causing cell lysis? or death when the bacteria tries to divide)
Penicllin works by inhibiting the formation of peptidoglycan cross links in the bacterial cell wall by directly competing for the reaction site (the [beta-lactam ring]? of penicillin is a chemical analogue for the enzyme that links the peptidoglycan molecules in bacteria) and thus preventing the bacteria from multiplying (or rather causing cell lysis? or death when the bacteria tries to divide). See optical isomerism.

Changed: 7c7
Antibiotic resistance to penicillin is now common amongst many hospital acquired bacteria. The resistance to penicillin has been partly (maybe mostly) due to the rise of beta-lactamase producing bacteria which secrete an enzyme that breaks down the beta-lactam ring of penicillin, rendering it harmless to the bacteria.
Antibiotic resistance to penicillin is now common amongst many hospital acquired bacteria. The resistance to penicillin has been partly (maybe mostly) due to the rise of beta-lactamase producing bacteria which secrete an enzyme that breaks down the beta-lactam ring of penicillin, rendering it harmless to the bacteria.

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