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Pinky and the Brain are Cartoon characters from the TV series Animaniacs. Later they starred in their own Cartoon call Pinky and the Brain and even later in Pinky, Elmira and The Brain.
The Brain is a genically enhanced mouse bent on taking over the work. He has super intelligence and develops elaborate plans to take over the world.
Pinky is also genically modified and is very stupid. Among his favourite words are NARF and ZOIT.