Phenothiazines are antipsychotic drugs. There are three groups: *I - Aliphatic compounds have a strong sedative effect, but moderate extrapyramidal and autonomic effects. *II - Piperidines have moderate sedative effects and fewer extrapyramidal effects than aliphatic compounds, but more autonomic effects. *III - Piperazines have few sedative effects, pronounced extrapyramidal effects, and less autonomic effects. |
Phenothiazines are antipsychotic drugs. There are three groups different by their chemical structure and their pharmacological effects:
|
Group | Sedative | Extrapyramidal | Autonomic |
Aliphatic compounds | strong | moderate | moderate |
Piperidines | moderate | weak | strong |
Piperazines | weak | strong | weak |