A
proteasome is a multi-
protein complex that can digest other proteins into short
polypeptides and
amino acids in an
ATP-driven reaction. The proteasome is hollow, providing an enclosed space for protein digestion.
For a description of the unit S, see Svedberg?. For A, see Angstrom.
26S proteasome
The 26S proteasome is used for the digestion of
ubiquitin-marked proteins. It consists of a 19S and a 20S unit. The 20S unit consists of 14 α and 14 β subunits. It is about 150 A long and 115 A wide.
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