The 'meaning' referred to is purpose, justification, not meaning in the sense that words have meaning. This is why responses such as 'life can't have a meaning, it's not a word' or 'look it up in a dictionary' are fallacious.
We can also separate this question into two different questions: one about the objective purpose of life, and the other about subjective purpose of life. The subjective purpose of life varies of course from person, and need not be considered any further.
Many deny that an objective purpose of anything is possible. Purposes, they argue, are purely subjective. Others claim that life has an objective purpose, though they differ as to what this purpose is, or where it comes from.
Over the millennia, philosophers have had much to say about this question--though philosophers do not fixate on it as much as popular conceptions might lead one to believe. Theories of value--of which there are very many indeed--can be and not sometimes are construed as theories of the meaning of life. Great philosophers such as Socrates, Plato, Aristotle, Descartes, Spinoza, and many others had clear views about what sort of life was best (and hence most meaningful). The existentialists addressed themselves to the question head-on. More recently, Robert Nozick discussed the question at great length in his Philosophical Explanations.
This needs to be expanded greatly.
Religion itself, it is often suggested, is a response to humanity's search for meaning or purpose. The notion here is that we do or ought to seek a higher purpose that will give our lives meaning.
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