A manuscript is usually preserved in form of a book, like for instance codex or roll. Historically manuscripts are have usually been written on either parchment, papyrus or paper.
In Library and Information Science, a manuscript can refer to any hand-written item in the collections of a library or archive?, e.g. archived letters or diary from a person.
In film and theatre, a manuscript, or script for short, is an author's or dramatist?'s text being used by a publisher for making a book (after editing?) or by a [theater company]? or film crew for making a performance?.
The word, manuscript, is often abbreviated to MS., plural MSS.