Of course it didn't take a prophet to see that this location would play an important role as the crossing point between two continents (Europe and Asia), and later a magnet for Africa and others as well, in terms of commerce, culture, diplomacy and strategy. As a strategic position again, Constantinoupolis, was able to control the passageway between Asia and Europe, as well as the passage from the Mediterranean Sea to the Euxinos Pontus.
In the 20th century the city, having passed into the hands of the Turks in 1453, was renamed Istanbul.
See also Roman Empire, Roman Emperors, Byzantine Empire and Byzantine Emperors.