Drugs used for this purpose have included alcohol, scopolamine, and sodium pentothal - all sedatives that interfere particularly with judgement and higher cognitive function. Whilst alcohol is used by this purpose by many individuals in a more innocent sense, it is apparently used by professionals in the areas as well. A book by a former Soviet KGB officer based in Washington, Washington Station, details the use of near-pure alcohol to verify that a Soviet agent was not compromised by US counter-intelligence services.
Whilst fictional accounts of intelligence interrogation gives these drugs near magical abilities, information obtained by publically-disclosed truth drugs has been shown to be highly unreliable, with subjects apparently freely mixing fact and fantasy. Therefore, interest in their use outside intelligence services has declined to negligible levels - though their use has been reexamined after the September 11, 2001 Terrorist Attacks. It is possible, but thought unlikely by experts in anaesthetics (the drugs most closely resembling truth drugs in common use), that intelligence services do have more effective such drugs at their disposal which they have not disclosed.
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